Name : CKIP-1 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3098838360
| Long name | ALEXA FLUOR 594 Conjugated, CKIP-1 Polyclonal Antibody |
| Also known as | Anti-CKIP-1 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CKIP-1 |
| Specificity | This is a highly specific antibody against CKIP-1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 60-110/409 |
| Subcellular location | Cell membrane, Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CKIP-1 |
| Gene ID Number | 51177 |
| Swiss Prot | Q53GL0 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Also implicated in PI3K-regulated muscle differentiation, Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival, Appears to target ATM to the plasma membrane, May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2), When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF, Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CKIP-1 OC120 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | CKIP-1 |
| Short name | CKIP-1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, CKIP-1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24310 |
| Gene | PLEKHO1 |
| Long gene name | pleckstrin homology domain containing O1 |
| Synonyms gene name | family O member 1 , pleckstrin homology domain containing |
| Locus | 1q21, 2 |
| Discovery year | 2005-11-28 |
| GenBank acession | AF073836 |
| Entrez gene record | 51177 |
| Pubmed identfication | 10799509 |
| RefSeq identity | NM_016274 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000012510 |