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CKIP-1 Antibody, Biotin Conjugated

CKIP-1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CKIP-1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCKIP-1
SpecificityThis is a highly specific antibody against CKIP-1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range60-110/409
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human CKIP-1
Gene ID number51177
Swiss ProtQ53GL0
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also implicated in PI3K-regulated muscle differentiation, Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival, Appears to target ATM to the plasma membrane, May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2), When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF, Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CKIP-1 OC120
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCKIP-1 Conjugated
Short name Conjugated, CKIP-1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CKIP-1 (Antibody to)
Alternative techniqueantibodies
Identity 24310
Gene PLEKHO1
Long gene name pleckstrin homology domain containing O1
Synonyms gene name family O member 1 , pleckstrin homology domain containing
Locus 1q21, 2
Discovery year 2005-11-28
GenBank acession AF073836
Entrez gene record 51177
Pubmed identfication 10799509
RefSeq identity NM_016274
Classification Pleckstrin homology domain containing
Havana BLAST/BLAT OTTHUMG00000012510

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