Name : Claudin 18 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6884772778
| Long name | Claudin 18 Primary Polyclonal Antibody |
| Also known as | Claudin 18 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Claudin 18 |
| Specificity | This is a highly specific antibody against Claudin 18 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Claudin 18 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Claudins, Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues (1), Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge (5), Occludin and Junction adhesion molecule (3), These proteins are important structural and functional components of tight junctions in paracellular transport (1, Three classes of proteins are known to localize to tight junctions, including the Claudins, which consist of four transmembrane domains and two extracellular loops make up tight junction strands (4), 2), Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions (6), The Claudin superfamily consists of many structurally related proteins in humans (1) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CLD18_HUMAN, CLDN18, Claudin-18, SFTA5, SFTPJ, Claudin 18 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Claudin 18 |
| Short name | Claudin 18 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Claudin 18 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2039 |
| Gene | CLDN18 |
| Long gene name | claudin 18 |
| Synonyms gene | SFTPJ |
| Synonyms gene name | surfactant associated protein J |
| Locus | 3q22, 3 |
| Discovery year | 2000-01-31 |
| GenBank acession | AF221069 AY102073 |
| Entrez gene record | 51208 |
| RefSeq identity | NM_001002026 |
| Classification | Claudins |
| Havana BLAST/BLAT | OTTHUMG00000159762 |