Name : Claudin 2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2216519562
| Long name | Claudin 2 Primary Polyclonal Antibody |
| Also known as | Claudin 2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Claudin 2 |
| Specificity | This is a highly specific antibody against Claudin 2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Claudin 2 |
| Gene ID number | 9075 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Able to form homopolymers of heteropolymers with other claudin family members, Claudin-2, Overexpression of claudin-2 is associated with a variety of diseases, The gene encoding claudin-2 maps to human chromosome X, also known as CLDN2 or SP82, claudin-2 plays an essential role in mediating calcium-independent cell-adhesion activity that is necessary for tight junction-specific obliteration of the intercellular space, colorectal cancer, further affirming the importance of claudin-2 in cell adhesion, gastrointestinal carcinomas and inflammatory bowel disease, including lung cancer, is a 230 amino acid multi-pass membrane protein that localizes to the cell junctions and belongs to the claudin superfamily, which contains nearly 153 million base pairs and houses over 1, 000 genes, The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CLD2_HUMAN, CLDN 2, CLDN2, Claudin2, OTTHUMP00000023793, SP 82, SP82, Claudin-2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Claudin 2 |
| Short name | Claudin 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Claudin 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2041 |
| Gene | CLDN2 |
| Long gene name | claudin 2 |
| Locus | Xq22, 3 |
| Discovery year | 1998-11-19 |
| GenBank acession | AK075405 |
| Entrez gene record | 9075 |
| Pubmed identfication | 9892664 |
| Classification | Claudins |
| Havana BLAST/BLAT | OTTHUMG00000022154 |
| Locus Specific Databases | Mental Retardation database |