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CLCA3 Antibody, FITC Conjugated

CLCA3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CLCA3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCLCA3
SpecificityThis is a highly specific antibody against CLCA3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from mouse CLCA3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Rat, Mouse
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CLCA1 is expressed as a precursor protein that is processed into two cell surface associated subunits and a group of proteins, CLCA1 is upregulated by interleukin-9 and regulates the expression of mucins, CLCA1 may provide a therapeutic target to control mucus overproduction in airway disease patients with cystic fibrosis, CLCA2 expression is downregulated in breast cancer, CLCA3 (known as Clca3 in mouse) is a structurally divergent member of the CLCA family that does not function as a channel protein, CLCA4 is a CLCA member that is expressed in human rectal mucosa, CLCA5 shows strong expression in eye and spleen, and CLCA6 is primarily expressed in intestine and stomach, display distinct tissue distribution patterns, therefore CLCA2 is thought to act as a tumor suppressor in normal cells, which includes the human homologs CLCA1 and CLCA2, The calcium-activated chloride channel (CLCA) protein family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCLCA3 Conjugated
Short name FITC Conjugated, CLCA3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CLCA3 (Antibody to)
Alternative techniqueantibodies
Identity 2017
Gene CLCA3P
Long gene name chloride channel accessory 3, pseudogene
Synonyms gene CLCA3
Synonyms gene name calcium activated, chloride channel, family member 3 chloride channel regulator 3
Locus 1p22, 3
Discovery year 1998-10-02
GenBank acession AF043976
Entrez gene record 9629
Pubmed identfication 10095065
RefSeq identity NM_004921
Classification Chloride channel accessory
Havana BLAST/BLAT OTTHUMG00000010258

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