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CLCNKB Antibody

CLCNKB Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCLCNKB Primary Polyclonal Antibody
Also known asCLCNKB PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCLCNKB
SpecificityThis is a highly specific antibody against CLCNKB
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CLCNKB
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla, CLC-KA plays a crucial role in urine concentration, CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments, CLCs regulate excitability in muscle and nerve cells, Mutations in this gene cause type III Barterâ, Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking, The gene encoding human CLC-KA maps to chromosome 1p36, The gene encoding human CLC-KB maps to chromosome 1p36, a critical component of all living cells, aid in organic solute transport, and maintain cellular volume, &euro, &trade, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s syndrome which is characterized by renal salt-wasting and low blood pressure
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CLCKB, CLCKB_HUMAN, CLCNKB, Chloride channel Kb, Chloride channel kidney B, Chloride channel protein ClC-Kb, Chloride channel voltage sensitive Kb, ClC K2, ClC-K2, ClCK2, MGC24087, OTTHUMP00000011120, OTTHUMP00000011121, RP11 5P18, hClC Kb, hClCKb, 8, Bartter syndrome type 3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCLCNKB
Short nameCLCNKB Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCLCNKB (Antibody to)
Alternative techniqueantibodies
Identity 2027
Gene CLCNKB
Long gene name chloride voltage-gated channel Kb
Synonyms gene name chloride channel Kb chloride channel, voltage-sensitive Kb
Synonyms hClC-Kb
Locus 1p36, 13
Discovery year 1995-12-11
GenBank acession AK098217
Entrez gene record 1188
RefSeq identity NM_000085
Classification Chloride voltage-gated channels
Havana BLAST/BLAT OTTHUMG00000009530

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