Name : CLCNKB Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5134060892
| Long name | ALEXA FLUOR 488 Conjugated, CLCNKB Polyclonal Antibody |
| Also known as | Anti-CLCNKB PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CLCNKB |
| Specificity | This is a highly specific antibody against CLCNKB |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CLCNKB |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla, CLC-KA plays a crucial role in urine concentration, CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments, CLCs regulate excitability in muscle and nerve cells, Mutations in this gene cause type III Barterâ, Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking, The gene encoding human CLC-KA maps to chromosome 1p36, The gene encoding human CLC-KB maps to chromosome 1p36, a critical component of all living cells, aid in organic solute transport, and maintain cellular volume, &euro, &trade, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s syndrome which is characterized by renal salt-wasting and low blood pressure |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | hClC-Kb |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CLCNKB Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | CLCNKB |
| Short name | CLCNKB Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, CLCNKB (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2027 |
| Gene | CLCNKB |
| Long gene name | chloride voltage-gated channel Kb |
| Synonyms gene name | chloride channel Kb chloride channel, voltage-sensitive Kb |
| Locus | 1p36, 13 |
| Discovery year | 1995-12-11 |
| GenBank acession | AK098217 |
| Entrez gene record | 1188 |
| RefSeq identity | NM_000085 |
| Classification | Chloride voltage-gated channels |
| Havana BLAST/BLAT | OTTHUMG00000009530 |