Name : CLCNKB Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5772739358
| Long name | Biotin Conjugated, CLCNKB Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CLCNKB |
| Specificity | This is a highly specific antibody against CLCNKB |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human CLCNKB |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla, CLC-KA plays a crucial role in urine concentration, CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments, CLCs regulate excitability in muscle and nerve cells, Mutations in this gene cause type III Barterâ, Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking, The gene encoding human CLC-KA maps to chromosome 1p36, The gene encoding human CLC-KB maps to chromosome 1p36, a critical component of all living cells, aid in organic solute transport, and maintain cellular volume, &euro, &trade, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s syndrome which is characterized by renal salt-wasting and low blood pressure |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | hClC-Kb |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CLCNKB Conjugated |
| Short name | Conjugated, CLCNKB Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, CLCNKB (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2027 |
| Gene | CLCNKB |
| Long gene name | chloride voltage-gated channel Kb |
| Synonyms gene name | chloride channel Kb chloride channel, voltage-sensitive Kb |
| Locus | 1p36, 13 |
| Discovery year | 1995-12-11 |
| GenBank acession | AK098217 |
| Entrez gene record | 1188 |
| RefSeq identity | NM_000085 |
| Classification | Chloride voltage-gated channels |
| Havana BLAST/BLAT | OTTHUMG00000009530 |