Name : CLCNKB Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6773739035
| Long name | FITC Conjugated, CLCNKB Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CLCNKB |
| Specificity | This is a highly specific antibody against CLCNKB |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human CLCNKB |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla, CLC-KA plays a crucial role in urine concentration, CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments, CLCs regulate excitability in muscle and nerve cells, Mutations in this gene cause type III Barterâ, Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking, The gene encoding human CLC-KA maps to chromosome 1p36, The gene encoding human CLC-KB maps to chromosome 1p36, a critical component of all living cells, aid in organic solute transport, and maintain cellular volume, &euro, &trade, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s syndrome which is characterized by renal salt-wasting and low blood pressure |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | hClC-Kb |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CLCNKB Conjugated |
| Short name | FITC Conjugated, CLCNKB Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, CLCNKB (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2027 |
| Gene | CLCNKB |
| Long gene name | chloride voltage-gated channel Kb |
| Synonyms gene name | chloride channel Kb chloride channel, voltage-sensitive Kb |
| Locus | 1p36, 13 |
| Discovery year | 1995-12-11 |
| GenBank acession | AK098217 |
| Entrez gene record | 1188 |
| RefSeq identity | NM_000085 |
| Classification | Chloride voltage-gated channels |
| Havana BLAST/BLAT | OTTHUMG00000009530 |