Name : CLN5 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8342631524
| Long name | Biotin Conjugated, CLN5 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CLN5 |
| Specificity | This is a highly specific antibody against CLN5 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human CLN5 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A single base duplication mutation in dog and cow CLN5 has been shown to cause NCL, CLN2 (encodeing the serine protease TPP1), CLN3, CLN5, CLN6 and CLN8, Mutations in six of these genes results in a distinct type of NCL-disease, NCL is characterized by atrophy of the brain and an accumulation of lysosome derived fluorescent bodies found in many cells, Symptoms of NCL include a failure of psychomotor development, The eight genes/proteins associated with NCL are designated CLN1-CLN8, a protein thiolesterase), also designated Batten disease, comprises a group of recessively inherited, especially neurons, impaired vision and premature death, progressive neurodegenerative diseases found in children, seizures, the six genes/proteins are CLN1 (encoding PPT1, Neuronal ceroid-lipofuscinose (NCL) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CLN5 Conjugated |
| Short name | Conjugated, CLN5 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, CLN5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2076 |
| Gene | CLN5 |
| Long gene name | ceroid-lipofuscinosis, neuronal 5 |
| Locus | 13q22, 3 |
| Discovery year | 1993-11-03 |
| Entrez gene record | 1203 |
| Pubmed identfication | 7942847 8661106 |
| RefSeq identity | NM_006493 |
| Havana BLAST/BLAT | OTTHUMG00000017100 |
| Locus Specific Databases | NCL Mutations LRG_692 , Neuronal Ceroid Lipofuscinoses |