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CLN5 Antibody, Biotin Conjugated

CLN5 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, CLN5 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCLN5
SpecificityThis is a highly specific antibody against CLN5
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CLN5
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A single base duplication mutation in dog and cow CLN5 has been shown to cause NCL, CLN2 (encodeing the serine protease TPP1), CLN3, CLN5, CLN6 and CLN8, Mutations in six of these genes results in a distinct type of NCL-disease, NCL is characterized by atrophy of the brain and an accumulation of lysosome derived fluorescent bodies found in many cells, Symptoms of NCL include a failure of psychomotor development, The eight genes/proteins associated with NCL are designated CLN1-CLN8, a protein thiolesterase), also designated Batten disease, comprises a group of recessively inherited, especially neurons, impaired vision and premature death, progressive neurodegenerative diseases found in children, seizures, the six genes/proteins are CLN1 (encoding PPT1, Neuronal ceroid-lipofuscinose (NCL)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCLN5 Conjugated
Short name Conjugated, CLN5 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CLN5 (Antibody to)
Alternative techniqueantibodies
Identity 2076
Gene CLN5
Long gene name ceroid-lipofuscinosis, neuronal 5
Locus 13q22, 3
Discovery year 1993-11-03
Entrez gene record 1203
Pubmed identfication 7942847 8661106
RefSeq identity NM_006493
Havana BLAST/BLAT OTTHUMG00000017100
Locus Specific Databases NCL Mutations LRG_692 , Neuronal Ceroid Lipofuscinoses

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