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CLN6 Antibody

CLN6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCLN6 Primary Polyclonal Antibody
Also known asCLN6 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCLN6
SpecificityThis is a highly specific antibody against CLN6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CLN6
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CLN6 is one of eight proteins, Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function, a 311 amino acid protein, a lysosomal storage disorder marked by progressive mental deterioration and blindness, causing the death of neurons, has seven predicted transmembrane domains and is conserved across vertebrates, including CLN1-8, part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, that are associated with NCL, CLN6
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CLN6 protein, CLN6_HUMAN, FLJ20561, Nclf, Protein CLN6, late infantile, neuronal 6, variant, Ceroid lipofuscinosis
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCLN6
Short nameCLN6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCLN6 (Antibody to)
Alternative techniqueantibodies
Identity 2077
Gene CLN6
Long gene name ceroid-lipofuscinosis, late infantile, neuronal 6, variant
Synonyms FLJ20561 HsT18960 nclf
Locus 15q23
Discovery year 1996-10-11
GenBank acession AK000568
Entrez gene record 54982
Pubmed identfication 9097964 11727201
RefSeq identity NM_017882
Havana BLAST/BLAT OTTHUMG00000133286
Locus Specific Databases NCL Mutations LRG_832 , Neuronal Ceroid Lipofuscinoses

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