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CLN6 Antibody, ALEXA FLUOR 488

CLN6 Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, CLN6 Polyclonal Antibody
Also known asAnti-CLN6 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCLN6
SpecificityThis is a highly specific antibody against CLN6
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CLN6
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen CLN6 is one of eight proteins, Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function, a 311 amino acid protein, a lysosomal storage disorder marked by progressive mental deterioration and blindness, causing the death of neurons, has seven predicted transmembrane domains and is conserved across vertebrates, including CLN1-8, part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, that are associated with NCL, CLN6
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms FLJ20561 HsT18960 nclf
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CLN6 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetCLN6
Short nameCLN6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, CLN6 (Antibody to)
Alternative techniqueantibodies
Identity 2077
Gene CLN6
Long gene name ceroid-lipofuscinosis, late infantile, neuronal 6, variant
Locus 15q23
Discovery year 1996-10-11
GenBank acession AK000568
Entrez gene record 54982
Pubmed identfication 9097964 11727201
RefSeq identity NM_017882
Havana BLAST/BLAT OTTHUMG00000133286
Locus Specific Databases NCL Mutations LRG_832 , Neuronal Ceroid Lipofuscinoses

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