Name : CLN6 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9850476503
| Long name | ALEXA FLUOR 488 Conjugated, CLN6 Polyclonal Antibody |
| Also known as | Anti-CLN6 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CLN6 |
| Specificity | This is a highly specific antibody against CLN6 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CLN6 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | CLN6 is one of eight proteins, Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function, a 311 amino acid protein, a lysosomal storage disorder marked by progressive mental deterioration and blindness, causing the death of neurons, has seven predicted transmembrane domains and is conserved across vertebrates, including CLN1-8, part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, that are associated with NCL, CLN6 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | FLJ20561 HsT18960 nclf |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CLN6 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | CLN6 |
| Short name | CLN6 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, CLN6 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2077 |
| Gene | CLN6 |
| Long gene name | ceroid-lipofuscinosis, late infantile, neuronal 6, variant |
| Locus | 15q23 |
| Discovery year | 1996-10-11 |
| GenBank acession | AK000568 |
| Entrez gene record | 54982 |
| Pubmed identfication | 9097964 11727201 |
| RefSeq identity | NM_017882 |
| Havana BLAST/BLAT | OTTHUMG00000133286 |
| Locus Specific Databases | NCL Mutations LRG_832 , Neuronal Ceroid Lipofuscinoses |