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CLN6 Antibody, FITC Conjugated

CLN6 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CLN6 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCLN6
SpecificityThis is a highly specific antibody against CLN6
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CLN6
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CLN6 is one of eight proteins, Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function, a 311 amino acid protein, a lysosomal storage disorder marked by progressive mental deterioration and blindness, causing the death of neurons, has seven predicted transmembrane domains and is conserved across vertebrates, including CLN1-8, part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, that are associated with NCL, CLN6
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FLJ20561 HsT18960 nclf
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCLN6 Conjugated
Short name FITC Conjugated, CLN6 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CLN6 (Antibody to)
Alternative techniqueantibodies
Identity 2077
Gene CLN6
Long gene name ceroid-lipofuscinosis, late infantile, neuronal 6, variant
Locus 15q23
Discovery year 1996-10-11
GenBank acession AK000568
Entrez gene record 54982
Pubmed identfication 9097964 11727201
RefSeq identity NM_017882
Havana BLAST/BLAT OTTHUMG00000133286
Locus Specific Databases NCL Mutations LRG_832 , Neuronal Ceroid Lipofuscinoses

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