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CLN8 Antibody, Cy3 Conjugated

CLN8 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, CLN8 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCLN8
SpecificityThis is a highly specific antibody against CLN8
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CLN8
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR), The CLN8 protein is one of eight proteins in the CLN family, a 286 amino acid transmembrane protein, a group of progressive neurodegenerative diseases found in children, but also partially to the ER-Golgi intermediate compartment (ERGIC), characterized by failure of psychomotor development, impaired vision, including CLN1-CLN7, localizes mainly to the endoplasmic reticulum, seizures and premature death, which are associated with NCL, CLN8
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms FLJ39417
Properties 1 of the CLN8 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCLN8 Conjugated
Short name Conjugated, CLN8 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, neuronal 8 (epilepsy, progressive with mental retardation) (Antibody to), ceroid-lipofuscinosis
Alternative techniqueantibodies
Alternative to gene target C8orf61 and EPMR, CLN8 and IDBG-5421 and ENSG00000182372 and 2055, CLN8 and IDBG-628376 and ENSBTAG00000008584 and 530874, Cln8 and IDBG-136384 and ENSMUSG00000026317 and 26889, Plasma membranes, neuronal 8 (epilepsy, progressive with mental retardation), this GO :0001306 and age-dependent response to oxidative stress and biological process this GO :0005739 and mitochondrion and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005793 and endoplasmic reticulum- this GO lgi intermediate compartment and cellular component this GO :0006644 and phospholipid metabolic process and biological process this GO :0006672 and ceramide metabolic process and biological process this GO :0006869 and lipid transport and biological process this GO :0007006 and mitochondrial membrane organization and biological process this GO :0007040 and lysosome organization and biological process this GO :0007399 and nervous system development and biological process this GO :0007601 and visual perception and biological process this GO :0007628 and adult walking behavior and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008219 and cell death and biological process this GO :0008306 and associative learning and biological process this GO :0008344 and adult locomotory behavior and biological process this GO :0008361 and regulation of cell size and biological process this GO :0008610 and lipid biosynthetic process and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0021522 and spinal cord motor neuron differentiation and biological process this GO :0021523 and somatic motor neuron differentiation and biological process this GO :0030163 and protein catabolic process and biological process this GO :0033116 and endoplasmic reticulum- this GO lgi intermediate compartment membrane and cellular component this GO :0035176 and social behavior and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044257 and cellular protein catabolic process and biological process this GO :0044265 and cellular macromolecule catabolic process and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045494 and photoreceptor cell maintenance and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0046513 and ceramide biosynthetic process and biological process this GO :0050881 and musculoskeletal movement and biological process this GO :0050884 and neuromuscular process controlling posture and biological process this GO :0050885 and neuromuscular process controlling balance and biological process this GO :0051348 and negative regulation of transferase activity and biological process this GO :0051935 and L-glutamate uptake involved in synaptic transmission and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060052 and neurofilament cytoskeleton organization and biological process, ceroid-lipofuscinosis
Identity 2079
Gene CLN8
Long gene name ceroid-lipofuscinosis, neuronal 8
Synonyms gene EPMR C8orf61
Synonyms gene name chromosome 8 open reading frame 61 epilepsy, progressive with mental retardation
Locus 8p23, 3
Discovery year 1993-12-15
GenBank acession AF123761
Entrez gene record 2055
Pubmed identfication 10508524 23160995
RefSeq identity NM_018941
Classification TLC domain containing
Havana BLAST/BLAT OTTHUMG00000090343
Locus Specific Databases NCL Mutations LRG_691 , Neuronal Ceroid Lipofuscinoses

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