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CLNS1A Antibody, FITC Conjugated

CLNS1A Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, CLNS1A Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCLNS1A
SpecificityThis is a highly specific antibody against CLNS1A
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CLNS1A/pICln
Gene ID number1207
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background JBP1), PRMT5 binds the Sm proteins via their arginine- and glycine-rich (RG) domains, The gene encoding human pICln maps to chromosome 11q14, This process is mediated by the survival of motor neuron (SMN) protein, a complex comprised of the type II methyltransferase PRMT5 (also designated Jak-binding protein 1, and is enhanced by modification of specific arginine residues in the Sm proteins to symmetrical dimethylarginines (sDMAs), and may play a role as a swelling-activated anion channel or a channel regulator in addition to its function in the methylosome, and two novel factors, pICln, pICln also acts as an inhibitor of SnRNP assembly by preventing specific interactions between Sm proteins required for the formation of the Sm core, pICln is a highly conserved, sDMA modification of Sm proteins is catalyzed by the methylosome, ubiquitously expressed protein that localizes primarily to the cytoplasm, while pICln binds the Sm domains, 1, The formation of the spliceosome includes the assembly of Sm proteins in an ordered manner onto snRNAs
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ICln
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCLNS1A Conjugated
Short name FITC Conjugated, CLNS1A Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CLNS1A (Antibody to)
Alternative techniqueantibodies
Identity 2080
Gene CLNS1A
Long gene name chloride nucleotide-sensitive channel 1A
Synonyms gene CLCI
Synonyms gene name 1A , chloride channel, nucleotide-sensitive
Synonyms name methylosome subunit pICln
Locus 11q14, 1
Discovery year 1997-10-16
GenBank acession U17899
Entrez gene record 1207
Pubmed identfication 7887970 8975725
RefSeq identity NM_001293
Havana BLAST/BLAT OTTHUMG00000165143

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