Name : CMKLR1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2759579252
| Long name | CMKLR1 Primary Polyclonal Antibody |
| Also known as | CMKLR1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CMKLR1 |
| Specificity | This is a highly specific antibody against CMKLR1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 175-222/371 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from mouse CMKLR1 |
| Gene ID number | 14747 |
| Swiss Prot | P97468 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rat, Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Interaction with RARRES2 induces activation of intracellular signaling molecules, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, Positively regulates adipogenesis and adipocyte metabolism, Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B (By similarity), enhancing of adipogenesis and angionesis, like reduction of immune responses, such as SKY, Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ChemR23, Chemokine-like receptor 1, Cmklr1, G-protein coupled receptor DEZ, Gpcr27, mcmklr1, DEZ |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CMKLR1 |
| Short name | CMKLR1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | chemokine-like receptor 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CHEMERINR and ChemR23 and DEZ and RVER1, CMKLR1 and IDBG-55274 and ENSG00000174600 and 1240, CMLKR1 and IDBG-647886 and ENSBTAG00000022039 and 615411, Cmklr1 and IDBG-191760 and ENSMUSG00000042190 and 14747, Plasma membranes, protein binding, this GO :0001501 and skeletal system development and biological process this GO :0004872 and receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0010759 and positive regulation of macrophage chemotaxis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0050848 and regulation of calcium-mediated signaling and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0005515: protein binding, this GO :0004930: G-protein coupled receptor activity, this GO :0004950: chemokine receptor activity, this GO :0005515: protein binding, chemokine-like receptor 1 |
| Identity | 2121 |
| Gene | CMKLR1 |
| Long gene name | chemerin chemokine-like receptor 1 |
| Synonyms gene name | chemokine-like receptor 1 |
| Synonyms | RVER1 |
| Synonyms name | resolvin E1 receptor chemerin receptor |
| Locus | 12q23, 3 |
| Discovery year | 1995-11-22 |
| GenBank acession | U79526 |
| Entrez gene record | 1240 |
| Classification | Chemerin receptor |
| Havana BLAST/BLAT | OTTHUMG00000169576 |