Name : CNOT2(Ser101) Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN3739346872
| Long name | Biotin Conjugated, CNOT2(Ser101) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CNOT2 Ser101 |
| Specificity | This is a highly specific antibody against CNOT2 Ser101 |
| Modification | Phosphorylation |
| Modification site | Ser101 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human CNOT2 around the phosphorylation site of Ser101 |
| Gene ID number | 4848 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | CNOT1, CNOT2 belongs to the CNOT2/3/5 family and is part of the CCR4-NOT complex, CNOT2) are involved in influencing nuclear hormone receptor activities, Increased expression of the CNOT2 subunit acts to strongly repress transcription by RNA polymerase II, Repression by the NOT-Box is sensitive to treatment with the histone deacetylase (HDAC) inhibitor trichostatin A, The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome, The CCR4-NOT complex is an evolutionarily conserved, This repressive effect is mediated by a conserved NOT-Box, Various subunits (e, multi-component complex known to be involved in transcription as well as mRNA degradation, which is located at the C-terminus of CNOT2 proteins, CNOT2 (CCR4-NOT transcription complex subunit 2) is a ubiquitous protein encoded by the human gene CNOT2, g |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | CDC36 NOT2H |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CNOT2(Ser101) Conjugated |
| Short name | Conjugated, CNOT2(Ser101) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, CNOT2(Ser101) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7878 |
| Gene | CNOT2 |
| Long gene name | CCR4-NOT transcription complex subunit 2 |
| Synonyms gene | NOT2 |
| Synonyms gene name | CCR4-NOT transcription complex, subunit 2 |
| Locus | 12q15 |
| Discovery year | 1996-07-19 |
| GenBank acession | AF180473 |
| Entrez gene record | 4848 |
| Pubmed identfication | 10637334 |
| Classification | CCR4-NOT transcription complex |
| Havana BLAST/BLAT | OTTHUMG00000169481 |