Name : CNOT2(Ser101) Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN9592638067
| Long name | Cy3 Conjugated, CNOT2(Ser101) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CNOT2 Ser101 |
| Specificity | This is a highly specific antibody against CNOT2 Ser101 |
| Modification | Phosphorylation |
| Modification site | Ser101 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human CNOT2 around the phosphorylation site of Ser101 |
| Gene ID number | 4848 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | CNOT1, CNOT2 belongs to the CNOT2/3/5 family and is part of the CCR4-NOT complex, CNOT2) are involved in influencing nuclear hormone receptor activities, Increased expression of the CNOT2 subunit acts to strongly repress transcription by RNA polymerase II, Repression by the NOT-Box is sensitive to treatment with the histone deacetylase (HDAC) inhibitor trichostatin A, The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome, The CCR4-NOT complex is an evolutionarily conserved, This repressive effect is mediated by a conserved NOT-Box, Various subunits (e, multi-component complex known to be involved in transcription as well as mRNA degradation, which is located at the C-terminus of CNOT2 proteins, CNOT2 (CCR4-NOT transcription complex subunit 2) is a ubiquitous protein encoded by the human gene CNOT2, g |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | CDC36 NOT2H |
| Properties | 1 of the CNOT2(Ser101) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CNOT2(Ser101) Conjugated |
| Short name | Conjugated, CNOT2(Ser101) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, CNOT2(Ser101) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7878 |
| Gene | CNOT2 |
| Long gene name | CCR4-NOT transcription complex subunit 2 |
| Synonyms gene | NOT2 |
| Synonyms gene name | CCR4-NOT transcription complex, subunit 2 |
| Locus | 12q15 |
| Discovery year | 1996-07-19 |
| GenBank acession | AF180473 |
| Entrez gene record | 4848 |
| Pubmed identfication | 10637334 |
| Classification | CCR4-NOT transcription complex |
| Havana BLAST/BLAT | OTTHUMG00000169481 |