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CNTF Receptor alpha Antibody

CNTF Receptor alpha Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCNTF Receptor alpha Primary Polyclonal Antibody
Also known asCNTF Receptor alpha PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCNTF Receptor alpha
SpecificityThis is a highly specific antibody against CNTF Receptor alpha
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range160-210/372
Subcellular locationCell membrane
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CNTFR Alpha
Gene ID number1271
Swiss ProtP26992
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Along with LIFR and gp130, Alternative splicing has been observed at this locus and two variants, CNTF Receptor alpha forms the heterotrimeric CNTF receptor complex, CNTF first binds to CNTF Recepror alpha, During signal transduction, Signal transduction stimulates gene expression, The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain, and this permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex, both encoding the same protein, cell survival or differentiation in a variety of neuronal cell types, have been identified, CNTF Receptor alpha is a receptor belonging to the cytokine superfamily of receptors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CNTF receptor subunit alpha, CNTFR, CNTFR-alpha, Ciliary neurotrophic factor receptor subunit alpha
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCNTF Receptor alpha
Short nameCNTF Receptor alpha Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameciliary neurotrophic factor Receptor a (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CNTF and IDBG-409278 and ENSG00000242689 and 1270, CNTF and IDBG-637978 and ENSBTAG00000003624 and 100848228, Cntf and IDBG-254935 and ENSMUSG00000079415 and 12803, Extracellular, HCNTF, growth factor activity, this GO :0005127 and ciliary neurotrophic factor receptor binding and molecular function this GO :0005138 and interleukin-6 receptor binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007165 and signal transduction and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0040007 and growth and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0046533 and negative regulation of photoreceptor cell differentiation and biological process this GO :0046668 and regulation of retinal cell programmed cell death and biological process this GO :0048644 and muscle organ morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0070120 and ciliary neurotrophic factor-mediated signaling pathway and biological process this GO :0097058 and CRLF-CLCF1 complex and cellular component, this GO :0005127: ciliary neurotrophic factor receptor binding, this GO :0005127: ciliary neurotrophic factor receptor binding and also this GO :0005138: interleukin-6 receptor binding and also this GO :0008083: growth factor activity, this GO :0005138: interleukin-6 receptor binding, this GO :0008083: growth factor activity, ciliary neurotrophic factor
Identity 2169
Gene CNTF
Long gene name ciliary neurotrophic factor
Synonyms HCNTF
Locus 11q12, 1
Discovery year 1991-01-07
GenBank acession BC068030
Entrez gene record 1270
Pubmed identfication 1840538 1714745
RefSeq identity NM_000614
Classification Interleukin 6 cytokine family
Havana BLAST/BLAT OTTHUMG00000137476
Locus Specific Databases ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

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