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COL1A2 Antibody

COL1A2 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCOL1A2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the COL1A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis COL1A2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P08123
PurityAntigen affinity
Description Dalgleish], Ehlers-Danlos syndrome type VIIB, Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Symptoms associated with mutations in this gene, Three transcripts, Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, [provided by R, and atypical Marfan syndrome, cornea, dermis and tendon, have been identified for this gene, however, idiopathic osteoporosis, recessive Ehlers-Danlos syndrome Classical type, resulting from the use of alternate polyadenylation signals, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity, This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain
ImmunogenA portion of amino acids 16-43 from the human protein was used as the immunogen for this COL1A2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the COL1A2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCOL1A2
Short nameCOL1A2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name a 2 (Antibody to), classification I, collagen
Alternative techniqueantibodies
Alternative to gene target COL1A2 and IDBG-27319 and ENSG00000164692 and 1278, COL1A2 and IDBG-629088 and ENSBTAG00000013472 and 282188, Col1a2 and IDBG-127903 and ENSMUSG00000029661 and 12843, Extracellular, OI4, alpha 2, bridging, bridging and also this GO :0042802: identical protein binding and also this GO :0046332: SMAD binding and also this GO :0046872: metal ion binding and also this GO :0048407: platelet-derived growth factor binding, bridging and molecular function this GO :0031012 and extracellular matrix and cellular component this GO :0042476 and odontogenesis and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043589 and skin morphogenesis and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0048407 and platelet-derived growth factor binding and molecular function this GO :0050900 and leukocyte migration and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070208 and protein heterotrimerization and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process, protein binding, this GO :0001501 and skeletal system development and biological process this GO :0001568 and blood vessel development and biological process this GO :0005201 and extracellular matrix structural constituent and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005584 and collagen type I and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030199 and collagen fibril organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0030674 and protein binding, this GO :0005201: extracellular matrix structural constituent, this GO :0005201: extracellular matrix structural constituent and also this GO :0005515: protein binding and also this GO :0030674: protein binding, this GO :0005515: protein binding, this GO :0030674: protein binding, this GO :0042802: identical protein binding, this GO :0046332: SMAD binding, this GO :0046872: metal ion binding, this GO :0048407: platelet-derived growth factor binding, type I, collagen
Identity 2198
Gene COL1A2
Long gene name collagen type I alpha 2 chain
Synonyms gene OI4
Synonyms gene name alpha 2 collagen type I alpha 2 , osteogenesis imperfecta type IV collagen, type I
Synonyms name alpha 2(I)-collagen alpha-2 collagen type I type I procollagen collagen I, alpha-2 chain , alpha-2 polypeptide collagen of skin, tendon and bone
Locus 7q21, 3
Discovery year 2001-06-22
GenBank acession Z74616
Entrez gene record 1278
Pubmed identfication 3857213 2897363
RefSeq identity NM_000089
Classification Collagens
Havana BLAST/BLAT OTTHUMG00000148675
Locus Specific Databases Osteogenesis Imperfecta Variant Database LRG_2

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