| Long name | COL2A1 Primary Polyclonal Antibody |
| Also known as | COL2A1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Collagen alpha-1(II) chain |
| Specificity | This is a highly specific antibody against Collagen alpha-1(II) chain |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 270-310/1487 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Collagen alpha-1(II) chain |
| Gene ID number | 1280 |
| Swiss Prot | P02458 |
| Tested Applications | IF(ICC) |
| Recommended dilutions | IF(ICC)(1:50-200) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces, Type II collagen is specific for cartilaginous tissues |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ANFH, Alpha-1 type II collagen, COL11A3, COL2A1, Collagen alpha-1(II) chain, SEDC, STL1, AOM |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | COL2A1 |
| Short name | COL2A1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | a 1 (Antibody to), classification II, collagen |
| Alternative technique | antibodies |
| Alternative to gene target | ANFH and AOM and COL11A3 and SEDC and STL1, COL2A1 and IDBG-29355 and ENSG00000139219 and 1280, COL2A1 and IDBG-632928 and ENSBTAG00000013155 and 407142, Col2a1 and IDBG-179337 and ENSMUSG00000022483 and 12824, Extracellular, alpha 1, platelet-derived growth factor binding, this GO :0001501 and skeletal system development and biological process this GO :0001502 and cartilage condensation and biological process this GO :0001503 and ossification and biological process this GO :0001894 and tissue homeostasis and biological process this GO :0001958 and endochondral ossification and biological process this GO :0002062 and chondrocyte differentiation and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0005201 and extracellular matrix structural constituent and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005581 and collagen trimer and cellular component this GO :0005585 and collagen type II and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0006029 and proteoglycan metabolic process and biological process this GO :0007411 and axon guidance and biological process this GO :0007417 and central nervous system development and biological process this GO :0007601 and visual perception and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030020 and extracellular matrix structural constituent conferring tensile strength and molecular function this GO :0030198 and extracellular matrix organization and biological process this GO :0030199 and collagen fibril organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0030903 and notochord development and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0035108 and limb morphogenesis and biological process this GO :0042472 and inner ear morphogenesis and biological process this GO :0042802 and identical protein binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0048407 and platelet-derived growth factor binding and molecular function this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048839 and inner ear development and biological process this GO :0051216 and cartilage development and biological process this GO :0060021 and palate development and biological process this GO :0060174 and limb bud formation and biological process this GO :0060272 and embryonic skeletal joint morphogenesis and biological process this GO :0060348 and bone development and biological process this GO :0060351 and cartilage development involved in endochondral bone morphogenesis and biological process this GO :0071599 and otic vesicle development and biological process this GO :0071773 and cellular response to BMP stimulus and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005201: extracellular matrix structural constituent, this GO :0005201: extracellular matrix structural constituent and also this GO :0005515: protein binding and also this GO :0030020: extracellular matrix structural constituent conferring tensile strength and also this GO :0042802: identical protein binding and also this GO :0046872: metal ion binding and also this GO :0048407: platelet-derived growth factor binding, this GO :0005515: protein binding, this GO :0030020: extracellular matrix structural constituent conferring tensile strength, this GO :0042802: identical protein binding, this GO :0046872: metal ion binding, this GO :0048407: platelet-derived growth factor binding, type II, collagen |
| Identity | 2200 |
| Gene | COL2A1 |
| Long gene name | collagen type II alpha 1 chain |
| Synonyms gene | SEDC AOM |
| Synonyms gene name | alpha 1 (primary osteoarthritis, alpha 1 collagen type II alpha 1 , collagen, congenital) arthroophthalmopathy, progressive (Stickler syndrome) collagen, spondyloepiphyseal dysplasia, type II, type II |
| Synonyms | STL1 |
| Locus | 12q13, 11 |
| Discovery year | 1986-01-01 |
| GenBank acession | X16468 |
| Entrez gene record | 1280 |
| Pubmed identfication | 1677770 |
| RefSeq identity | NM_001844 |
| Classification | Collagens |
| Havana BLAST/BLAT | OTTHUMG00000149896 |
| Locus Specific Databases | Belgium , Ghent, LOVD - Center for Medical Genetics |
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