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COMP Antibody , Biotin Conjugated

COMP Antibody , Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, COMP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCOMP
SpecificityThis is a highly specific antibody against COMP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range265-300/757
Subcellular locationSecreted
SourceKLH conjugated synthetic peptide derived from human COMP
Gene ID number1311
Swiss ProtP49747
Tested applicationsWB
Recommended dilutionsWB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BIRC2, BIRC5 and XIAP), Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors, Could play a role in the pathogenesis of osteoarthritis, Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli, Maintains this phenotype of VSMCs by interacting with ITGA7 (By similarity), Potent suppressor of apoptosis in both primary chondrocytes and transformed cells, Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MED THBS5
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCOMP Conjugated
Short nameCOMP Antibody Conjugated
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, cartilage oli this GO meric matrix protein (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, COMP and IDBG-38816 and ENSG00000105664 and 1311, Comp and IDBG-162847 and ENSMUSG00000031849 and 12845, EDM1 and EPD1 and MED and PSACH and THBS5, Extracellular, heparan sulfate proteoglycan binding, this GO :0001501 and skeletal system development and biological process this GO :0002020 and protease binding and molecular function this GO :0003417 and growth plate cartilage development and biological process this GO :0005201 and extracellular matrix structural constituent and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0008201 and heparin binding and molecular function this GO :0009887 and organ morphogenesis and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043395 and heparan sulfate proteoglycan binding and molecular function this GO :0060173 and limb development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0002020: protease binding, this GO :0002020: protease binding and also this GO :0005201: extracellular matrix structural constituent and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0008201: heparin binding and also this GO :0043395: heparan sulfate proteoglycan binding, this GO :0005201: extracellular matrix structural constituent, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0005518: collagen binding, this GO :0008201: heparin binding, this GO :0043395: heparan sulfate proteoglycan binding, 3034 and IDBG-641613 and ENSBTAG00000004630 and 281088, cartilage oli this GO meric matrix protein
Identity 2227
Gene COMP
Long gene name cartilage oligomeric matrix protein
Synonyms gene PSACH EDM1 EPD1
Synonyms gene name cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple)
Synonyms name thrombospondin-5
Locus 19p13, 11
Discovery year 1994-05-24
GenBank acession L32137
Entrez gene record 1311
Pubmed identfication 7713493 8307576
RefSeq identity NM_000095
Havana BLAST/BLAT OTTHUMG00000169318

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