Name : Complement fragment 3c Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN3296942105
| Long name | FITC Conjugated, Complement fragment 3c Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Complement fragment 3c |
| Specificity | This is a highly specific antibody against Complement fragment 3c |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Secreted |
| Source | KLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1 |
| Gene ID number | 718 |
| Swiss Prot | P01024 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Pig, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | ARRB2-mediated internalization and recycling of C5AR2 (PubMed:837664, Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, After activation C3b can bind covalently, Appears to stimulate TG synthesis via activation of the PLC, C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation, C3a anaphylatoxin is a mediator of local inflammatory process, Derived from proteolytic degradation of complement C3, In chronic inflammation, It induces the contraction of smooth muscle, Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways, Ligand for C5AR2, MAPK and AKT signaling pathways, Promotes the phosphorylation, PubMed:1432298, PubMed:15833747, PubMed:16333141, PubMed:1961575), PubMed:29953, PubMed:959512, acts as a chemoattractant for neutrophils (By similarity), increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes, regulating fat storage and playing a role in postprandial TG clearance, to cell surface carbohydrates or immune aggregates, via its reactive thioester, C3 plays a central role in the activation of the complement system |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | AHUS5, ARMD9, C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3a, C3b, CPAMD1, Complement C3, HEL-S-62p, ASP |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Complement 3c Conjugated |
| Short name | FITC Conjugated, Complement 3c Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Isotype | Complement fragments, Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small, IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion, bp DNA fragments are common, coli expressed, single chain variable fragments can be E, Antibody fragments and scFv fragments |
| Label | FITC |
| Alternative name | fluorecein coupled, Complement fragment 3c (Antibody to) |
| Alternative technique | antibodies |