| Long name | COMT Primary Polyclonal Antibody |
| Also known as | COMT PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | COMT |
| Specificity | This is a highly specific antibody against COMT |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 160-205/271 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human COMT |
| Gene ID number | 1312 |
| Swiss Prot | P21964 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Also shortens the biological half-lives of certain neuroactive drugs, alpha-methyl DOPA and isoproterenol, and thereby the inactivation, like L-DOPA, of catecholamine neurotransmitters and catechol hormones, Catalyzes the O-methylation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | COMT, Catechol O-methyltransferase, HEL-S-98n |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | COMT |
| Short name | COMT Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | catechol-O-methyltransferase (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | COMT and IDBG-1506 and ENSG00000093010 and 1312, COMT and IDBG-638156 and ENSBTAG00000019516 and 618278, Comt and IDBG-141739 and ENSMUSG00000000326 and 12846, HEL-S-98n, Plasma membranes, catechol O-methyltransferase activity, this GO :0000287 and magnesium ion binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006584 and catecholamine metabolic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007565 and female pregnancy and biological process this GO :0007612 and learning and biological process this GO :0007614 and short-term memory and biological process this GO :0008171 and O-methyltransferase activity and molecular function this GO :0008210 and estrogen metabolic process and biological process this GO :0009712 and catechol-containing compound metabolic process and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016036 and cellular response to phosphate starvation and biological process this GO :0016206 and catechol O-methyltransferase activity and molecular function this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0032259 and methylation and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032502 and developmental process and biological process this GO :0035814 and negative regulation of renal sodium excretion and biological process this GO :0042135 and neurotransmitter catabolic process and biological process this GO :0042136 and neurotransmitter biosynthetic process and biological process this GO :0042417 and dopamine metabolic process and biological process this GO :0042420 and dopamine catabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0043197 and dendritic spine and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0044297 and cell body and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0045963 and negative regulation of dopamine metabolic process and biological process this GO :0048265 and response to pain and biological process this GO :0048609 and multicellular organismal reproductive process and biological process this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0050668 and positive regulation of homocysteine metabolic process and biological process this GO :0051930 and regulation of sensory perception of pain and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0008171: O-methyltransferase activity and also this GO :0016206: catechol O-methyltransferase activity, this GO :0008171: O-methyltransferase activity, this GO :0016206: catechol O-methyltransferase activity, catechol-O-methyltransferase |
| Identity | 2228 |
| Gene | COMT |
| Long gene name | catechol-O-methyltransferase |
| Locus | 22q11, 21 |
| Discovery year | 2001-06-22 |
| Entrez gene record | 1312 |
| Pubmed identfication | 1572656 |
| RefSeq identity | NM_000754 |
| Havana BLAST/BLAT | OTTHUMG00000150529 |
| Locus Specific Databases | LRG_1010 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue