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COPS3 Antibody, FITC Conjugated

COPS3 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, COPS3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCOPS3
SpecificityThis is a highly specific antibody against COPS3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human COPS3
Gene ID number8533
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CSA or DDB2, CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, ITPK1 and IRF8/ICSBP, IkappaBalpha/NFKBIA, The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, The complex is also involved in phosphorylation of p53/TP53, a complex involved in various cellular and developmental processes, c-jun/JUN, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, possibly via its association with CK2 and PKD kinases, respectively, Component of the COP9 signalosome complex (CSN)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms SGN3 CSN3
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCOPS3 Conjugated
Short name FITC Conjugated, COPS3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, COPS3 (Antibody to)
Alternative techniqueantibodies
Identity 2239
Gene COPS3
Long gene name COP9 signalosome subunit 3
Synonyms gene name Arabidopsis, COP9 (constitutive photomorphogenic, homolog) subunit 3 COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
Locus 17p11, 2
Discovery year 1998-10-06
GenBank acession AF031647
Entrez gene record 8533
Pubmed identfication 9535219 10191102
Classification COP9 signalosome
Havana BLAST/BLAT OTTHUMG00000059281

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