Name : Cortactin (401CT8.6.3) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :328
SKU : GEN8565694812
| Long name | 3) Monoclonal Antibody, 6, Cortactin (401CT8 |
| Also known as | 3) Monoclonal Antibody, 6, Cortactin (401CT8 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Cortactin |
| Specificity | This is a highly specific antibody against Cortactin |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 3, 401CT8, 6 |
| Source | Purified His-tagged Cortactin protein(Fragment) was used to produced this monoclonal antibody |
| Gene ID number | 2017 |
| Swiss Prot | Q14247 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:1000~8000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In complex with ABL1 and MYLK regulates cortical actin-based cytoskeletal rearrangement critical to sphingosine 1-phosphate (S1P)-mediated endothelial cell (EC) barrier enhancement (PubMed:20861316), Plays a role in focal adhesion assembly and turnover (By similarity), Plays a role in intracellular protein transport and endocytosis, Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity), Plays a role in the formation of lamellipodia and in cell migration, Plays a role in the invasiveness of cancer cells, Plays a role in the regulation of neuron morphology, Required for stabilization of KCNH1 channels at the cell membrane (PubMed:23144454), Through its interaction with CTTNBP2, and in modulating the levels of potassium channels present at the cell membrane (PubMed:17959782), and the formation of metastases (PubMed:16636290), axon growth and formation of neuronal growth cones (By similarity), involved in the regulation of neuronal spine density (By similarity), Contributes to the organization of the actin cytoskeleton and cell shape (PubMed:21296879) |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Amplaxin, CTTN, Oncogene EMS1, Src substrate cortactin, EMS1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 3) Monoclonal, 6, Cortactin (401CT8 |
| Short name | 3) Monoclonal Antibody, 6, Cortactin (401CT8 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 3) monoclonal (Antibody to), 6, Cortactin (401CT8 |
| Alternative technique | antibodies |