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Cortactin (401CT8.6.3) Monoclonal Antibody

Cortactin (401CT8.6.3) Monoclonal Antibody size: 0.1ml 328

Price 328
Size 0.1ml
Long name3) Monoclonal Antibody, 6, Cortactin (401CT8
Also known as3) Monoclonal Antibody, 6, Cortactin (401CT8
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCortactin
SpecificityThis is a highly specific antibody against Cortactin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number3, 401CT8, 6
SourcePurified His-tagged Cortactin protein(Fragment) was used to produced this monoclonal antibody
Gene ID number2017
Swiss ProtQ14247
Tested ApplicationsWB
Recommended dilutionsWB(1:1000~8000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In complex with ABL1 and MYLK regulates cortical actin-based cytoskeletal rearrangement critical to sphingosine 1-phosphate (S1P)-mediated endothelial cell (EC) barrier enhancement (PubMed:20861316), Plays a role in focal adhesion assembly and turnover (By similarity), Plays a role in intracellular protein transport and endocytosis, Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity), Plays a role in the formation of lamellipodia and in cell migration, Plays a role in the invasiveness of cancer cells, Plays a role in the regulation of neuron morphology, Required for stabilization of KCNH1 channels at the cell membrane (PubMed:23144454), Through its interaction with CTTNBP2, and in modulating the levels of potassium channels present at the cell membrane (PubMed:17959782), and the formation of metastases (PubMed:16636290), axon growth and formation of neuronal growth cones (By similarity), involved in the regulation of neuronal spine density (By similarity), Contributes to the organization of the actin cytoskeleton and cell shape (PubMed:21296879)
Purification method09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Amplaxin, CTTN, Oncogene EMS1, Src substrate cortactin, EMS1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target3) Monoclonal, 6, Cortactin (401CT8
Short name3) Monoclonal Antibody, 6, Cortactin (401CT8
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name3) monoclonal (Antibody to), 6, Cortactin (401CT8
Alternative techniqueantibodies

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