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CPA3/MC-CPA Antibody

CPA3/MC-CPA Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCPA3/MC-CPA Primary Polyclonal Antibody
Also known asCPA3/MC-CPA PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCPA3/MC-CPA
SpecificityThis is a highly specific antibody against CPA3/MC-CPA
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPA3/MC-CPA
Gene ID number1359
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CPA3, MC-CPA is stored as an active enzyme in the granule and is released, MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues, Mast cell carboxypeptidase A (MC-CPA), The MC-CPA gene, The optimum pH of MC-CPA is between neutral and basic, a part of the peptidase M14 family, along with other inflammatory mediators, along with trytases and chymases, depending upon the substrate, is a highly conserved metalloprotease localized to the secretory granules, resides on chromosome 3 and contains 11 exons, upon mast cell degranulation, Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CBPA3_HUMAN, Carboxypeptidase A3, Cpa3, MC CPA, MC-CPA, Mast cell carboxypeptidase A, carboxypeptidase A3 mast cell, mast cell carboxypeptidase A3, carboxypeptidase A
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCPA3/MC-CPA
Short nameCPA3/MC-CPA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namecarboxypeptidase A3 (mast cell)/MC-CPA (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CPA3 and IDBG-60396 and ENSG00000163751 and 1359, CPA3 and IDBG-637892 and ENSBTAG00000015008 and 528454, Cpa3 and IDBG-133537 and ENSMUSG00000001865 and 12873, Extracellular, MC-CPA, this GO :0002002 and regulation of angiotensin levels in blood and biological process this GO :0002003 and angiotensin maturation and biological process this GO :0004180 and carboxypeptidase activity and molecular function this GO :0004181 and metallocarboxypeptidase activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0006508 and proteolysis and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0030133 and transport vesicle and cellular component this GO :0030141 and secretory granule and cellular component this GO :0044267 and cellular protein metabolic process and biological process, this GO :0004180: carboxypeptidase activity, this GO :0004180: carboxypeptidase activity and also this GO :0004181: metallocarboxypeptidase activity and also this GO :0008233: peptidase activity and also this GO :0008270: zinc ion binding, this GO :0004181: metallocarboxypeptidase activity, this GO :0008233: peptidase activity, this GO :0008270: zinc ion binding, zinc ion binding, carboxypeptidase A3 (mast cell)
Identity 2298
Gene CPA3
Long gene name carboxypeptidase A3
Synonyms gene name carboxypeptidase A3 (mast cell)
Synonyms name mast cell carboxypeptidase A tissue carboxypeptidase A
Locus 3q24
Discovery year 1990-06-13
Entrez gene record 1359
RefSeq identity NM_001870
Classification Carboxypeptidases
Havana BLAST/BLAT OTTHUMG00000159526

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