Name : CPA3/MC-CPA Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3501744168
| Long name | ALEXA FLUOR 350 Conjugated, CPA3/MC-CPA Polyclonal Antibody |
| Also known as | Anti-CPA3/MC-CPA PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CPA3/MC-CPA |
| Specificity | This is a highly specific antibody against CPA3/MC-CPA |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPA3/MC-CPA |
| Gene ID Number | 1359 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | CPA3, MC-CPA is stored as an active enzyme in the granule and is released, MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues, Mast cell carboxypeptidase A (MC-CPA), The MC-CPA gene, The optimum pH of MC-CPA is between neutral and basic, a part of the peptidase M14 family, along with other inflammatory mediators, along with trytases and chymases, depending upon the substrate, is a highly conserved metalloprotease localized to the secretory granules, resides on chromosome 3 and contains 11 exons, upon mast cell degranulation, Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | CPA3/MC-CPA |
| Short name | CPA3/MC-CPA Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, carboxypeptidase A3 (mast cell)/MC-CPA (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CPA3 and IDBG-60396 and ENSG00000163751 and 1359, CPA3 and IDBG-637892 and ENSBTAG00000015008 and 528454, Cpa3 and IDBG-133537 and ENSMUSG00000001865 and 12873, Extracellular, MC-CPA, this GO :0002002 and regulation of angiotensin levels in blood and biological process this GO :0002003 and angiotensin maturation and biological process this GO :0004180 and carboxypeptidase activity and molecular function this GO :0004181 and metallocarboxypeptidase activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0006508 and proteolysis and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0030133 and transport vesicle and cellular component this GO :0030141 and secretory granule and cellular component this GO :0044267 and cellular protein metabolic process and biological process, this GO :0004180: carboxypeptidase activity, this GO :0004180: carboxypeptidase activity and also this GO :0004181: metallocarboxypeptidase activity and also this GO :0008233: peptidase activity and also this GO :0008270: zinc ion binding, this GO :0004181: metallocarboxypeptidase activity, this GO :0008233: peptidase activity, this GO :0008270: zinc ion binding, zinc ion binding, carboxypeptidase A3 (mast cell) |
| Identity | 2298 |
| Gene | CPA3 |
| Long gene name | carboxypeptidase A3 |
| Synonyms gene name | carboxypeptidase A3 (mast cell) |
| Synonyms name | mast cell carboxypeptidase A tissue carboxypeptidase A |
| Locus | 3q24 |
| Discovery year | 1990-06-13 |
| Entrez gene record | 1359 |
| RefSeq identity | NM_001870 |
| Classification | Carboxypeptidases |
| Havana BLAST/BLAT | OTTHUMG00000159526 |