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CPB2 Antibody

CPB2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCPB2 Primary Polyclonal Antibody
Also known asCPB2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCPB2
SpecificityThis is a highly specific antibody against CPB2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPB2
Gene ID number1361
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, Being activated by thrombin-thrombomodulin complex during blood coagulation, Elevated concentration in blood is considered as a risk factor for venous thrombosis, High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease, It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues, The concentration in plasma of healthy people is 5-10 ug/ml, This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot, and decreased levels are found in chronic liver disease, it exerts carboxypeptidase activity, pI 5, which is necessary for plasminogen binding to fibrin, 0), This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CP B2, CPB 2, CPB2, CPU, Carboxypeptidase B2, Carboxypeptidase U, CarboxypeptidaseB2, CarboxypeptidaseU, PCPB, Plasma carboxypeptidase B, Plasma carboxypeptidase B2, Procarboxypeptidase B, Procarboxypeptidase R, Procarboxypeptidase U, TAFI, Thrombin activable fibrinolysis inhibitor, Thrombin activatable fibrinolysis inhibitor, Carboxypeptidase B like protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCPB2
Short nameCPB2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCPB2 (Antibody to)
Alternative techniqueantibodies
Identity 2300
Gene CPB2
Long gene name carboxypeptidase B2
Synonyms gene name carboxypeptidase B2 (plasma, carboxypeptidase U) carboxypeptidase B2 (plasma)
Synonyms CPU PCPB TAFI
Synonyms name thrombin-activatable fibrinolysis inhibitor carboxypeptidase U plasma carboxypeptidase B carboxypeptidase R
Locus 13q14, 13
Discovery year 1992-04-10
GenBank acession M75106
Entrez gene record 1361
Pubmed identfication 1939207 1427879
RefSeq identity NM_001872
Classification Carboxypeptidases
Havana BLAST/BLAT OTTHUMG00000016867

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