Name : CPB2 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8284248147
| Long name | ALEXA FLUOR 594 Conjugated, CPB2 Polyclonal Antibody |
| Also known as | Anti-CPB2 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CPB2 |
| Specificity | This is a highly specific antibody against CPB2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPB2 |
| Gene ID Number | 1361 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, Being activated by thrombin-thrombomodulin complex during blood coagulation, Elevated concentration in blood is considered as a risk factor for venous thrombosis, High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease, It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues, The concentration in plasma of healthy people is 5-10 ug/ml, This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot, and decreased levels are found in chronic liver disease, it exerts carboxypeptidase activity, pI 5, which is necessary for plasminogen binding to fibrin, 0), This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CPU PCPB TAFI |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | CPB2 |
| Short name | CPB2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, CPB2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2300 |
| Gene | CPB2 |
| Long gene name | carboxypeptidase B2 |
| Synonyms gene name | carboxypeptidase B2 (plasma, carboxypeptidase U) carboxypeptidase B2 (plasma) |
| Synonyms name | thrombin-activatable fibrinolysis inhibitor carboxypeptidase U plasma carboxypeptidase B carboxypeptidase R |
| Locus | 13q14, 13 |
| Discovery year | 1992-04-10 |
| GenBank acession | M75106 |
| Entrez gene record | 1361 |
| Pubmed identfication | 1939207 1427879 |
| RefSeq identity | NM_001872 |
| Classification | Carboxypeptidases |
| Havana BLAST/BLAT | OTTHUMG00000016867 |