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CPLX1 Antibody, ALEXA FLUOR 594

CPLX1 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, CPLX1 Polyclonal Antibody
Also known asAnti-CPLX1 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCPLX1
SpecificityThis is a highly specific antibody against CPLX1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPLX1
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A progressive loss of Complexin 2 occurs in the brains of mice carrying the Huntington disease mutation, Changes in the neurotransmitter release might contribute to the motor, Complexin 1 and Complexin 2 are expressed in presynaptic terminals of inhibitory and excitatory hippocampal neurons, Complexin 2 may play a role in LTP (long term potentiation) following tetanic stimulation, Complexins are important regulators of transmitter release at a late step in calcium dependent neurotransmitter release or immediately after the calcium-triggering step of fast synchronous transmitter release and preceding vesicle fusion, Complexins promote SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) precomplex formation by binding to synaxin with its a-helical domain, Neurons lacking complexins show reduced transmitter release efficiency due to decreased calcium sensitivity of the synaptic secretion process, also designated Synaphin 1 and Synaphin 2, an autosomal dominant neurodegenerative disorder, and in cytoplasmic pools during early stages of development, contain an a-helical middle domain of approximately 58 amino acids, emotional and cognitive dysfunctions seen in these mice, respectively, Complexin 1 and Complexin 2
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms CPX-I
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetCPLX1
Short nameCPLX1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, complexin 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CPLX1 and IDBG-6120 and ENSG00000168993 and 10815, CPX-I and CPX1, Cplx1 and IDBG-188148 and ENSMUSG00000033615 and 12889, Cytoplasm, syntaxin binding, this GO :0000149 and SNARE binding and molecular function this GO :0005326 and neurotransmitter transporter activity and molecular function this GO :0005829 and cytosol and cellular component this GO :0006836 and neurotransmitter transport and biological process this GO :0006887 and exocytosis and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007269 and neurotransmitter secretion and biological process this GO :0014047 and glutamate secretion and biological process this GO :0016079 and synaptic vesicle exocytosis and biological process this GO :0017075 and syntaxin-1 binding and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0030073 and insulin secretion and biological process this GO :0030425 and dendrite and cellular component this GO :0031201 and SNARE complex and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043234 and protein complex and cellular component this GO :0045202 and synapse and cellular component this GO :0070032 and synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex and cellular component, this GO :0000149: SNARE binding, this GO :0000149: SNARE binding and also this GO :0005326: neurotransmitter transporter activity and also this GO :0017075: syntaxin-1 binding and also this GO :0019905: syntaxin binding, this GO :0005326: neurotransmitter transporter activity, this GO :0017075: syntaxin-1 binding, this GO :0019905: syntaxin binding, complexin 1
Identity 2309
Gene CPLX1
Long gene name complexin 1
Locus 4p16, 3
Discovery year 1999-09-09
GenBank acession AF022383
Entrez gene record 10815
Pubmed identfication 7553862
Havana BLAST/BLAT OTTHUMG00000160005

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