CPLX1 Antibody, Biotin Conjugated

CPLX1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, CPLX1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	CPLX1
Specificity	This is a highly specific antibody against CPLX1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human CPLX1
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	A progressive loss of Complexin 2 occurs in the brains of mice carrying the Huntington disease mutation, Changes in the neurotransmitter release might contribute to the motor, Complexin 1 and Complexin 2 are expressed in presynaptic terminals of inhibitory and excitatory hippocampal neurons, Complexin 2 may play a role in LTP (long term potentiation) following tetanic stimulation, Complexins are important regulators of transmitter release at a late step in calcium dependent neurotransmitter release or immediately after the calcium-triggering step of fast synchronous transmitter release and preceding vesicle fusion, Complexins promote SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) precomplex formation by binding to synaxin with its a-helical domain, Neurons lacking complexins show reduced transmitter release efficiency due to decreased calcium sensitivity of the synaptic secretion process, also designated Synaphin 1 and Synaphin 2, an autosomal dominant neurodegenerative disorder, and in cytoplasmic pools during early stages of development, contain an a-helical middle domain of approximately 58 amino acids, emotional and cognitive dysfunctions seen in these mice, respectively, Complexin 1 and Complexin 2
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	CPX-I
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	CPLX1 Conjugated
Short name	Conjugated, CPLX1 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, complexin 1 (Antibody to)
Alternative technique	antibodies
Alternative to gene target	CPLX1 and IDBG-6120 and ENSG00000168993 and 10815, CPX-I and CPX1, Cplx1 and IDBG-188148 and ENSMUSG00000033615 and 12889, Cytoplasm, syntaxin binding, this GO :0000149 and SNARE binding and molecular function this GO :0005326 and neurotransmitter transporter activity and molecular function this GO :0005829 and cytosol and cellular component this GO :0006836 and neurotransmitter transport and biological process this GO :0006887 and exocytosis and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007269 and neurotransmitter secretion and biological process this GO :0014047 and glutamate secretion and biological process this GO :0016079 and synaptic vesicle exocytosis and biological process this GO :0017075 and syntaxin-1 binding and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0030073 and insulin secretion and biological process this GO :0030425 and dendrite and cellular component this GO :0031201 and SNARE complex and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043234 and protein complex and cellular component this GO :0045202 and synapse and cellular component this GO :0070032 and synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex and cellular component, this GO :0000149: SNARE binding, this GO :0000149: SNARE binding and also this GO :0005326: neurotransmitter transporter activity and also this GO :0017075: syntaxin-1 binding and also this GO :0019905: syntaxin binding, this GO :0005326: neurotransmitter transporter activity, this GO :0017075: syntaxin-1 binding, this GO :0019905: syntaxin binding, complexin 1
Identity	2309
Gene	CPLX1
Long gene name	complexin 1
Locus	4p16, 3
Discovery year	1999-09-09
GenBank acession	AF022383
Entrez gene record	10815
Pubmed identfication	7553862
Havana BLAST/BLAT	OTTHUMG00000160005

CPLX1 Antibody, Biotin Conjugated

CPLX1 Antibody, Biotin Conjugated size: 0.1ml 333

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