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CPN2 Antibody

CPN2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCPN2 Primary Polyclonal Antibody
Also known asCPN2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCPN2
SpecificityThis is a highly specific antibody against CPN2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CPN2
Gene ID number1370
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Because of the highly conserved active sites and the possible redundant functions of carboxypeptidases, By removing only one amino acid, CPN has the ability to change peptide activity and receptor binding, CPN is a member of a larger family of carboxypeptidases, CPN2, It consists of 2 identical 83 kDa regulatory subunits (CPN2) and 2 identical 50 kDa catalytic subunits (CPN1), It is a 280 kDa tetrameric glycoprotein that is synthesized by the liver and secreted into the plasma, Under some circumstances it may be an allosteric modifier of the catalytic subunit, and cleaves carboxy-terminal arginines and lysines from peptides found in the bloodstream such as complement anaphylatoxins, and creatine kinase MM (CK-MM), binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation, it has been difficult to elucidate the role of CPN in disease processes, kinins, many of which also cleave arginine and lysine, the 83 kDa subunit, CPN2 is a zinc metalloprotease
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ACBP, CPN-2, CPN2, CPN2_HUMAN, Carboxypeptidase N 83 kDa chain, Carboxypeptidase N large subunit, Carboxypeptidase N regulatory subunit, Carboxypeptidase N subunit 2 [Precursor], carboxypeptidase N, polypeptide 2, CPN 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCPN2
Short nameCPN2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCPN2 (Antibody to)
Alternative techniqueantibodies
Identity 2315
Gene CPNE2
Long gene name copine 2
Synonyms gene name copine II
Synonyms CPN2
Locus 16q13
Discovery year 1999-02-09
Entrez gene record 221184
Pubmed identfication 9430674
RefSeq identity NM_152727
Classification Copines
Havana BLAST/BLAT OTTHUMG00000133471

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