Name : CREB-1(Ser121) Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN7636962831
| Long name | ALEXA FLUOR 350 Conjugated, CREB-1(Ser121) Polyclonal Antibody |
| Also known as | Anti-CREB-1Ser121 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CREB-1Ser121 |
| Specificity | This is a highly specific antibody against CREB-1Ser121 |
| Modification | Phosphorylation |
| Modification Site | Ser121 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human CREB-1 around the phosphorylation site of Ser121 [ TD(p-S)QK] |
| Gene ID Number | 1385 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | ATF-1, Although each of the ATF/CREB proteins bind CREs in their homodimeric form, CREB-2, It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), TGACCTCA, The best characterized members of this gene family include CREB-1, both within the ATF/CREB family and with members of the AP-1 transcription factor family, in cerain instances they also bind as heterodimers, these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains, which may reprecent a CREB co-activator, ATF-2, ATF-3and ATF-4, The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | Active transcription factor CREB, CREB, CREB 1, CREB1, CREB1, CREB1_HUMAN, MGC9284, Transactivator protein, cAMP response element binding protein, cAMP responsive element binding protein 1, p-CREB-1Ser121, pCREB-1Ser121, CREBSer121 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | CREB-1(Ser121) |
| Short name | CREB-1(Ser121) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, CREB-1(Ser121) (Antibody to) |
| Alternative technique | antibodies |