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Crk Antibody p38

Crk Antibody p38 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCrk p38
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the Crk antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis Crk antibodyis to be used only for research purposes and not for diagnostics
Gene ID #1398
PurityAntigen affinity
Description It is mapped to 17p13, The N-terminal SH2 domain of Crk functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation, The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, The protein participates in the Reelin signaling cascade downstream of DAB1, This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins, Two alternative transcripts encoding different isoforms with distinct biological activity have been described, also known as p38, is a protein that in humans is encoded by the CRK gene, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction, 3, CRK
ImmunogenHuman partial recombinant protein (AA 2-246) was used as the immunogen for this Crk antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Crk antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCrk p38
Short nameCrk Antibody p38
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCrk (Antibody to) p38
Alternative techniqueantibodies

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