Name : Crk II (Tyr221) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN5461774743
| Long name | Crk II (Tyr221) Primary Polyclonal Antibody |
| Also known as | Crk II (Tyr221) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Crk isoform II Tyr221 |
| Specificity | This is a highly specific antibody against Crk isoform II Tyr221 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Tyr221 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human Crk p38 around the phosphorylation site of Tyr221 [GP(p-Y)AQ] |
| Gene ID number | 1398 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Crk-II has less transforming activity than Crk-I, Crk-II mediates attachment-induced MAPK8 activation, Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4, May regulate the EFNA5-EPHA3 signaling, membrane ruffling and cell motility in a Rac-dependent manner, The Crk-I and Crk-II forms differ in their biological activities |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CRK, Proto-oncogene c-Crk, p38, Adapter molecule crk |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Crk II (Tyr221) |
| Short name | Crk II (Tyr221) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Crk II (Tyr221) (Antibody to) |
| Alternative technique | antibodies |