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Crk p38 Antibody, ALEXA FLUOR 350

Crk p38 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, Crk p38 Polyclonal Antibody
Also known asAnti-Crk p38 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCrk p38
SpecificityThis is a highly specific antibody against Crk p38
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Crk p38 /CrkII
Gene ID Number1398
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers, CrkI and CrkII are produced from the same crk gene by alternative splicing, In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth, It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation, The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction, Crk p38 (CrkII) is an isoform of the protein Crk, Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms Adapter molecule crk, Avian sarcoma virus CT10 v crk oncogene homolog, CRK isoform 2, CRK isoform II, CRKII, CrkII, Proto oncogene C crk, p38, v crk avian sarcoma virus CT10 oncogene homolog, v crk sarcoma virus CT10 oncogene homolog, v crk sarcoma virus CT10 oncogene homolog avian, CRK
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetCrk p38
Short nameCrk p38 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Crk p38 (Antibody to)
Alternative techniqueantibodies

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