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Crk p38 Antibody, Cy7 Conjugated

Crk p38 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, Crk p38 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCrk p38
SpecificityThis is a highly specific antibody against Crk p38
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Crk p38 /CrkII
Gene ID number1398
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers, CrkI and CrkII are produced from the same crk gene by alternative splicing, In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth, It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation, The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction, Crk p38 (CrkII) is an isoform of the protein Crk, Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms Adapter molecule crk, Avian sarcoma virus CT10 v crk oncogene homolog, CRK isoform 2, CRK isoform II, CRKII, CrkII, Proto oncogene C crk, p38, v crk avian sarcoma virus CT10 oncogene homolog, v crk sarcoma virus CT10 oncogene homolog, v crk sarcoma virus CT10 oncogene homolog avian, CRK
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetCrk p38 Conjugated
Short name Conjugated, Crk p38 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, Crk p38 (Antibody to)
Alternative techniqueantibodies

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