Name : Crkl Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4211914596
| Long name | Crkl Primary Polyclonal Antibody |
| Also known as | Crkl PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Crkl |
| Specificity | This is a highly specific antibody against Crkl |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 235-285/303 |
| Subcellular location | Intracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Crkl |
| Gene ID number | 1399 |
| Swiss Prot | P46109 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Crkl has oncogenic potential, Crkl is a substitute of BCR ABL tyrosine kinase, In addition, Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CRKL, Crk-like protein |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Crkl |
| Short name | Crkl Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | v-crk sarcoma virus CT10 oncogene homolog (avian)-like (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2363 |
| Gene | CRKL |
| Long gene name | CRK like proto-oncogene, adaptor protein |
| Synonyms gene name | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| Locus | 22q11, 21 |
| Discovery year | 1994-09-14 |
| Entrez gene record | 1399 |
| Pubmed identfication | 8361759 8798523 |
| RefSeq identity | NM_005207 |
| Classification | SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000150807 |