Filters

CRMP2/TOAD64 Antibody

CRMP2/TOAD64 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCRMP2/TOAD64 Primary Polyclonal Antibody
Also known asCRMP2/TOAD64 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCRMP2/TOAD64
SpecificityThis is a highly specific antibody against CRMP2/TOAD64
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRMP2
Gene ID number1808
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly, CRMP2 is upregulated after axotomy, CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification, CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome, CRMPs localize to the lamellipodia and filopodia of axonal growth cones, Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease, Interaction studies have implicated phospholipase D2 (PLD2), Moreover, The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction, and appears to increase the formation of axon-type processes from hippocampal neurons, and intersectin in CRMP function, suggesting a role in axon guidance, the cytosolic tyrosine kinase Fes, Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CRAM, CRMP 2, CRMP-2, CRMP2, Collapsin response mediator protein hCRMP 2, DHPRP 2, DHPRP2, DPYL 2, DPYL2, DPYL2_HUMAN, DPYSL 2, DRP 2, DRP-2, DRP2, Dihydr pyrimidinase 2, Dihydropyrimidinase 2, Dihydropyrimidinase like 2, Dihydropyrimidinase like 2 long form, Dihydropyrimidinase related protein 2, Dihydropyrimidinase-related protein 2, Dpysl2, Musunc 33, Musunc33, N2A3, TOAD 64, TOAD64, ULIP 2 protein, ULIP-2, Ulip2, Unc-33-like phosphoprotein 2, Collapsin response mediator protein 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCRMP2/TOAD64
Short nameCRMP2/TOAD64 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCRMP2/TOAD64 (Antibody to)
Alternative techniqueantibodies
Identity 3014
Gene DPYSL2
Long gene name dihydropyrimidinase like 2
Synonyms gene name dihydropyrimidinase-like 2
Synonyms DRP-2 DHPRP2 CRMP2 DRP2
Locus 8p21, 2
Discovery year 1997-02-27
GenBank acession D78013
Entrez gene record 1808
Pubmed identfication 8973361
RefSeq identity NM_001386
Havana BLAST/BLAT OTTHUMG00000099439

Similar products

Subscribe to our Newsletter