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CRTAP Antibody, ALEXA FLUOR 594

CRTAP Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, CRTAP Polyclonal Antibody
Also known asAnti-CRTAP PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCRTAP
SpecificityThis is a highly specific antibody against CRTAP
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRTAP
Gene ID Number10491
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, CRTAP is widely expressed with predominant expression in articular chondrocytes, In the endoplasmic reticulum (ER), It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation, Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B, OI, OI type 7 is a mild form of this disorder, also known as brittle bone disease, extracellular fibril assembly and intracellular trafficking, is characterized by bone fragility and susceptibility to fractures, the major structural proteins of skin and bone, while OI type 2B is a neonatal lethal condition, CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms CASP LEPREL3 P3H5
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetCRTAP
Short nameCRTAP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, CRTAP (Antibody to)
Alternative techniqueantibodies
Identity 2379
Gene CRTAP
Long gene name cartilage associated protein
Synonyms name leprecan-like 3 prolyl 3-hydroxylase family member 5 (non-enzymatic)
Locus 3p22, 3
Discovery year 1999-10-19
GenBank acession AJ006470
Entrez gene record 10491
Pubmed identfication 9217321 10429950
Havana BLAST/BLAT OTTHUMG00000130746
Locus Specific Databases Osteogenesis Imperfecta Variant Database LRG_4

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