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CRTAP Antibody, Cy7 Conjugated

CRTAP Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, CRTAP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCRTAP
SpecificityThis is a highly specific antibody against CRTAP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CRTAP
Gene ID number10491
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, CRTAP is widely expressed with predominant expression in articular chondrocytes, In the endoplasmic reticulum (ER), It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation, Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B, OI, OI type 7 is a mild form of this disorder, also known as brittle bone disease, extracellular fibril assembly and intracellular trafficking, is characterized by bone fragility and susceptibility to fractures, the major structural proteins of skin and bone, while OI type 2B is a neonatal lethal condition, CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms CASP LEPREL3 P3H5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetCRTAP Conjugated
Short name Conjugated, CRTAP Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, CRTAP (Antibody to)
Alternative techniqueantibodies
Identity 2379
Gene CRTAP
Long gene name cartilage associated protein
Synonyms name leprecan-like 3 prolyl 3-hydroxylase family member 5 (non-enzymatic)
Locus 3p22, 3
Discovery year 1999-10-19
GenBank acession AJ006470
Entrez gene record 10491
Pubmed identfication 9217321 10429950
Havana BLAST/BLAT OTTHUMG00000130746
Locus Specific Databases Osteogenesis Imperfecta Variant Database LRG_4

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