Filters

CRTAP Antibody, FITC Conjugated

CRTAP Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CRTAP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCRTAP
SpecificityThis is a highly specific antibody against CRTAP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CRTAP
Gene ID number10491
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, CRTAP is widely expressed with predominant expression in articular chondrocytes, In the endoplasmic reticulum (ER), It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation, Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B, OI, OI type 7 is a mild form of this disorder, also known as brittle bone disease, extracellular fibril assembly and intracellular trafficking, is characterized by bone fragility and susceptibility to fractures, the major structural proteins of skin and bone, while OI type 2B is a neonatal lethal condition, CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CASP LEPREL3 P3H5
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCRTAP Conjugated
Short name FITC Conjugated, CRTAP Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CRTAP (Antibody to)
Alternative techniqueantibodies
Identity 2379
Gene CRTAP
Long gene name cartilage associated protein
Synonyms name leprecan-like 3 prolyl 3-hydroxylase family member 5 (non-enzymatic)
Locus 3p22, 3
Discovery year 1999-10-19
GenBank acession AJ006470
Entrez gene record 10491
Pubmed identfication 9217321 10429950
Havana BLAST/BLAT OTTHUMG00000130746
Locus Specific Databases Osteogenesis Imperfecta Variant Database LRG_4

Similar products

Subscribe to our Newsletter