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CSEN (Ser63) Antibody, ALEXA FLUOR 594

CSEN (Ser63) Antibody, ALEXA FLUOR 594 size: 100ul 350

Price 350
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, CSEN (Ser63) Polyclonal Antibody
Also known asAnti-CSEN Ser63 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCSEN Ser63
SpecificityThis is a highly specific antibody against CSEN Ser63
ModificationPhosphorylation
Modification SiteSer63
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationMembrane bound
SourceKLH conjugated synthetic phosphopeptide derived from human CSEN around the phosphorylation site of Ser63
Gene ID Number30818
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen DRE is a regulatory sequence that silences basal transcription and is localized to the promoter region of the gene encoding human prodynorphin, DREAM forms functional homotetramers that are required for the interaction with the DRE, DREAM has been shown to inhibit transcription of other proteins containing DRE-like motifs, DREAM transcripts are detected in brain, This association is highly influenced by calcium, an opioid peptide involved in memory acquisition and pain, and it is expressed as a nuclear protein, as an increase in Ca2+ directly inhibits DREAM binding and thereby blocks the repressor activity of DREAM, including the gene encoding for the AP-1 transcription factor c-Fos, suggesting that DREAM may influence a wide variety of cellular genes, thymus and thyroid gland, CSEN is a Ca2+-regulated transcriptional repressor that specifically binds to the downstream regulatory elements (DRE)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms DREAM KCHIP3
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetCSEN (Ser63)
Short nameCSEN (Ser63) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, CSEN (Ser63) (Antibody to)
Alternative techniqueantibodies
Identity 15523
Gene KCNIP3
Long gene name potassium voltage-gated channel interacting protein 3
Synonyms gene CSEN
Synonyms gene name EF hand transcription factor Kv channel interacting protein 3, calsenilin, calsenilin , presenilin-binding protein
Synonyms name calsenilin
Locus 2q11, 1
Discovery year 2001-05-24
GenBank acession AF199599
Entrez gene record 30818
Pubmed identfication 9771752 10078534
RefSeq identity NM_013434
Classification Potassium voltage-gated channel regulatory subunits EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000130392

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