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CSEN (Ser63) Antibody, Cy5 Conjugated

CSEN (Ser63) Antibody, Cy5 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, CSEN (Ser63) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCSEN Ser63
SpecificityThis is a highly specific antibody against CSEN Ser63
ModificationPhosphorylation
Modification siteSer63
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationMembrane bound
SourceKLH conjugated synthetic phosphopeptide derived from human CSEN around the phosphorylation site of Ser63
Gene ID number30818
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background DRE is a regulatory sequence that silences basal transcription and is localized to the promoter region of the gene encoding human prodynorphin, DREAM forms functional homotetramers that are required for the interaction with the DRE, DREAM has been shown to inhibit transcription of other proteins containing DRE-like motifs, DREAM transcripts are detected in brain, This association is highly influenced by calcium, an opioid peptide involved in memory acquisition and pain, and it is expressed as a nuclear protein, as an increase in Ca2+ directly inhibits DREAM binding and thereby blocks the repressor activity of DREAM, including the gene encoding for the AP-1 transcription factor c-Fos, suggesting that DREAM may influence a wide variety of cellular genes, thymus and thyroid gland, CSEN is a Ca2+-regulated transcriptional repressor that specifically binds to the downstream regulatory elements (DRE)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms DREAM KCHIP3
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCSEN (Ser63) Conjugated
Short name Conjugated, CSEN (Ser63) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, CSEN (Ser63) (Antibody to)
Alternative techniqueantibodies
Identity 15523
Gene KCNIP3
Long gene name potassium voltage-gated channel interacting protein 3
Synonyms gene CSEN
Synonyms gene name EF hand transcription factor Kv channel interacting protein 3, calsenilin, calsenilin , presenilin-binding protein
Synonyms name calsenilin
Locus 2q11, 1
Discovery year 2001-05-24
GenBank acession AF199599
Entrez gene record 30818
Pubmed identfication 9771752 10078534
RefSeq identity NM_013434
Classification Potassium voltage-gated channel regulatory subunits EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000130392

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