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CSK Antibody

CSK Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCSK Primary Polyclonal Antibody
Also known asCSK PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCSK
SpecificityThis is a highly specific antibody against CSK
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CSK
Gene ID number1445
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences, Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites, In the case of Src p60, Y527 is this tyrosine, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart, however, All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C SRC kinase, C src Tyrosine Kinase, C-SRC kinase, CSK, CSK_HUMAN, CYTOPLASMIC TYROSINE KINASE, Csk A, EC 2, MGC112926, MGC117393, MGC154049, P60 Src, Protein tyrosine kinase CYL, Protein-tyrosine kinase CYL, Proto oncogene tyrosine protein kinase, Tyrosine protein kinase CSK, Tyrosine-protein kinase CSK, c-src tyrosine kinase, zgc:154049, 2, 7, 10, C SRC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCSK
Short nameCSK Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCSK (Antibody to)
Alternative techniqueantibodies
Identity 2444
Gene CSK
Long gene name CSK, non-receptor tyrosine kinase
Synonyms gene name c-src tyrosine kinase
Locus 15q24, 1
Discovery year 1992-03-20
Entrez gene record 1445
Pubmed identfication 1377109
RefSeq identity NM_004383
Classification SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000142814

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