Name : CstF-64 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9823460341
| Long name | ALEXA FLUOR 594 Conjugated, CstF-64 Polyclonal Antibody |
| Also known as | Anti-CstF-64 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CstF-64 |
| Specificity | This is a highly specific antibody against CstF-64 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CSTF2T/CstF-64 |
| Gene ID Number | 23283 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | CstF-64 contains an RNA binding domain and is responsible for the RNA binding activity of CstF, CstF-64 is expressed in all somatic cells and in pre- and postmeiotic, However, The first step, The gene encoding CstF-64 (designated CSTF2) maps to the X chromosome, The increase in CstF-64 concentration during B cell activation switches IgM heavy chain mRNA expression from membrane-bound to secreted forms, a heterotrimer that is composed of three distinct subunits, a large variant of CstF-64, and promotes the germ cell pattern of polyadenylation, but not meiotic, called t CstF-64, endonucleolytic cleavage of polyadenylation substrates, germ cells, is abundantly expressed in meiotic and postmeiotic cells in the testis and to a lesser extent in the brain, requires CstF (cleavage stimulation factor), suggesting that CstF-64 plays a key role in regulating IgM heavy chain expression during B cell differentiation, whereas t CstF-64 is encoded by an autosomal gene, Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | CstF-64 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | CstF-64 |
| Short name | CstF-64 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, CstF-64 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 2484 |
| Gene | CSTF2 |
| Long gene name | cleavage stimulation factor subunit 2 |
| Synonyms gene name | 3', 3', 64kD cleavage stimulation factor, cleavage stimulation factor, pre-RNA, pre-RNA, subunit 2, subunit 2 |
| Locus | Xq22, 1 |
| Discovery year | 1994-12-12 |
| GenBank acession | BC017712 |
| Entrez gene record | 1478 |
| Pubmed identfication | 1741396 |
| RefSeq identity | NM_001325 |
| Classification | RNA binding motif containing |
| Havana BLAST/BLAT | OTTHUMG00000022709 |
| Locus Specific Databases | Mental Retardation database |