Name : CT27 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9076991406
| Long name | CT27 Primary Polyclonal Antibody |
| Also known as | CT27 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CT27 |
| Specificity | This is a highly specific antibody against CT27 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BORIS/CT27 |
| Gene ID number | 140690 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, In association with DNMT1 and DNMT3B, Plays a key role in gene imprinting in male germline, Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters, Seems to act as tumor suppressor, This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity), by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR), involved in activation of BAG1 gene expression by binding to its promoter, leading to methylate histone H4 'Arg-3' to form H4R3sme2, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers, Testis-specific DNA binding protein responsible for insulator function |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Brother of the regulator of imprinted sites, CCCTC binding factor zinc finger protein like, CCCTC-binding factor, CT27, CTCF T, CTCF paralog, CTCF-like protein, CTCFL, CTCFL_HUMAN, Cancer/testis antigen 27, HMG 1L1, HMGB1L1, Putative high mobility group protein 1 like 1, Putative high mobility group protein B1 like 1, Transcriptional repressor CTCFL, Zinc finger protein CTCF-T, BORIS like protein |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CT27 |
| Short name | CT27 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CT27 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16234 |
| Gene | CTCFL |
| Long gene name | CCCTC-binding factor like |
| Synonyms gene name | CCCTC-binding factor (zinc finger protein)-like |
| Synonyms | dJ579F20, 2 BORIS CT27 |
| Synonyms name | cancer/testis antigen 27 transcriptional repressor CTCFL |
| Locus | 20q13, 31 |
| Discovery year | 2001-07-17 |
| Entrez gene record | 140690 |
| RefSeq identity | NM_080618 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000032829 |