Name : CT27 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN2460850500
| Long name | FITC Conjugated, CT27 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CT27 |
| Specificity | This is a highly specific antibody against CT27 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human BORIS/CT27 |
| Gene ID number | 140690 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, In association with DNMT1 and DNMT3B, Plays a key role in gene imprinting in male germline, Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters, Seems to act as tumor suppressor, This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity), by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR), involved in activation of BAG1 gene expression by binding to its promoter, leading to methylate histone H4 'Arg-3' to form H4R3sme2, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers, Testis-specific DNA binding protein responsible for insulator function |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | dJ579F20, 2 BORIS CT27 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CT27 Conjugated |
| Short name | FITC Conjugated, CT27 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, CT27 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16234 |
| Gene | CTCFL |
| Long gene name | CCCTC-binding factor like |
| Synonyms gene name | CCCTC-binding factor (zinc finger protein)-like |
| Synonyms name | cancer/testis antigen 27 transcriptional repressor CTCFL |
| Locus | 20q13, 31 |
| Discovery year | 2001-07-17 |
| Entrez gene record | 140690 |
| RefSeq identity | NM_080618 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000032829 |