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Cullin 1 Antibody / CUL1

Cullin 1 Antibody / CUL1 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCullin 1 / CUL1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions1-0, 5ug/ml, Western blot: 0
NotesOptimal dilution of the Cullin 1 antibody should be determined by the researcher
Intented useThis Cullin 1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q13616
PurityAntigen affinity
Description 3, 4A, Human cullin 1, This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, This protein plays an important role in protein degradation and protein ubiquitination, also known as CUL1, and 5, but not the other closely related cullins 2, is a human protein and gene from cullin family, selectively interacts with human SKP1, signal transduction and transcription, which mediates the ubiquitination of proteins involved in cell cycle progression, Cullin 1
ImmunogenAmino acids 457-770 of human Cullin 1 were used as the immunogen for the Cullin 1 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cullin 1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
Localization cytoplasmic, Nuclear
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCullin 1 / CUL1
Short nameCullin 1 Antibody / CUL1
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCullin 1 (Antibody to) / cullin 1
Alternative techniqueantibodies
Alternative to gene target BT, CUL1 and IDBG-46918 and ENSG00000055130 and 8454, Cul1 and IDBG-143474 and ENSMUSG00000029686 and 26965, nuclei, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006513 and protein monoubiquitination and biological process this GO :0006915 and apoptotic process and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0008283 and cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0016032 and viral process and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0019005 and SCF ubiquitin ligase complex and cellular component this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0031146 and SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0031461 and cullin-RING ubiquitin ligase complex and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0031625: ubiquitin protein ligase binding, this GO :0031625: ubiquitin protein ligase binding, ubiquitin protein ligase binding, 36789 and IDBG-647000 and ENSBTAG00000047294 and, cullin 1
Identity 2551
Gene CUL1
Long gene name cullin 1
Locus 7q36, 1
Discovery year 1998-10-29
GenBank acession U58087
Entrez gene record 8454
Pubmed identfication 8681378
RefSeq identity NM_003592
Classification Cullins SCF complex
Havana BLAST/BLAT OTTHUMG00000152776

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